NRAS is detected as a mutational cancer driver
NRAS reports
Gene details
NRAS |
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Ensembl ID
ENSG00000213281
Transcript ID ENST00000369535 Protein ID ENSP00000358548 |
Cancer types where is driver
21
Cohorts where is driver 37 Mutated samples 777 Mutations 886 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
CM (Cutaneous melanoma of the skin) | 43 | 39 | 90.70 |
L (Lymphoid cancer) | 2 | 2 | 100.00 |
LK (Leukemia) | 44 | 43 | 97.73 |
MM (Multiple myeloma) | 36 | 33 | 91.67 |
SKIN (Skin cancer) | 2 | 0 | 0.00 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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