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NRAS CM ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
1:114713908:C Q61R missense_variant 1.00 114
1:114713909:T Q61K missense_variant 1.00 88
1:114713908:A Q61L missense_variant 1.00 21
1:114716124:G G13R missense_variant 1.00 5
1:114713907:G Q61H missense_variant 1.00 5
1:114716126:T G12D missense_variant 1.00 4
1:114716127:G G12R missense_variant 1.00 4
1:114713907:A Q61H missense_variant 1.00 4
1:114716126:G G12A missense_variant 1.00 2
1:114716123:T G13D missense_variant 1.00 2
1:114716127:A G12C missense_variant 1.00 2
1:114713909:A Q61* stop_gained 1.00 1
1:114713906:T E62K missense_variant 1.00 1
1:114713887:G R68T missense_variant 0.95 1
1:114713908:G Q61P missense_variant 1.00 0
1:114713905:G E62A missense_variant 1.00 0
1:114713905:C E62G missense_variant 1.00 0
1:114713905:A E62V missense_variant 1.00 0
1:114713909:C Q61E missense_variant 1.00 0
1:114716127:T G12S missense_variant 1.00 0
1:114716123:A G13V missense_variant 1.00 0
1:114716123:G G13A missense_variant 1.00 0
1:114716124:A G13C missense_variant 1.00 0
1:114716124:T G13S missense_variant 1.00 0
1:114716126:A G12V missense_variant 1.00 0
1:114713906:G E62Q missense_variant 1.00 0
1:114713904:A E62D missense_variant 1.00 0
1:114713904:G E62D missense_variant 1.00 0
1:114713906:A E62* stop_gained 1.00 0
1:114713887:A R68I missense_variant 0.95 0
1:114713887:T R68K missense_variant 0.95 0
1:114713886:A R68S missense_variant 0.90 0
1:114713886:G R68S missense_variant 0.90 0
1:114713888:C R68G missense_variant 0.90 0
1:114713888:A R68* stop_gained 0.73 0
In silico saturation mutagenesis
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Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(CM) Cutaneous melanoma of the skin CM 0.90 0.10