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NRAS MM ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
1:114713908:C Q61R missense_variant 1.00 93
1:114713909:T Q61K missense_variant 1.00 73
1:114716124:G G13R missense_variant 1.00 31
1:114713907:G Q61H missense_variant 1.00 13
1:114716126:T G12D missense_variant 1.00 12
1:114713907:A Q61H missense_variant 1.00 12
1:114713908:A Q61L missense_variant 1.00 10
1:114716123:T G13D missense_variant 1.00 10
1:114713900:C Y64D missense_variant 1.00 9
1:114716126:G G12A missense_variant 1.00 4
1:114716127:T G12S missense_variant 1.00 4
1:114713900:T Y64N missense_variant 1.00 3
1:114713908:G Q61P missense_variant 1.00 1
1:114713914:C A59G missense_variant 1.00 1
1:114716124:A G13C missense_variant 1.00 1
1:114716127:G G12R missense_variant 1.00 1
1:114716127:A G12C missense_variant 1.00 1
1:114716126:A G12V missense_variant 1.00 1
1:114716124:T G13S missense_variant 1.00 1
1:114713906:G E62Q missense_variant 1.00 1
1:114713832:T N86K missense_variant 0.94 1
1:114713905:G E62A missense_variant 1.00 0
1:114713905:A E62V missense_variant 1.00 0
1:114713905:C E62G missense_variant 1.00 0
1:114713914:T A59D missense_variant 1.00 0
1:114713909:C Q61E missense_variant 1.00 0
1:114713914:A A59V missense_variant 1.00 0
1:114716123:A G13V missense_variant 1.00 0
1:114716123:G G13A missense_variant 1.00 0
1:114713900:G Y64H missense_variant 1.00 0
1:114713904:A E62D missense_variant 1.00 0
1:114713904:G E62D missense_variant 1.00 0
1:114713909:A Q61* stop_gained 1.00 0
1:114713906:T E62K missense_variant 1.00 0
1:114713906:A E62* stop_gained 0.97 0
1:114713832:C N86K missense_variant 0.94 0
1:114713899:G Y64S missense_variant 0.90 0
1:114713899:A Y64F missense_variant 0.90 0
1:114713899:C Y64C missense_variant 0.90 0
1:114713833:A N86I missense_variant 0.87 0
1:114713834:A N86Y missense_variant 0.87 0
1:114713833:G N86T missense_variant 0.87 0
1:114713833:C N86S missense_variant 0.87 0
1:114713834:G N86H missense_variant 0.87 0
1:114713834:C N86D missense_variant 0.87 0
1:114713915:A A59S missense_variant 0.76 0
1:114713915:T A59T missense_variant 0.76 0
1:114713915:G A59P missense_variant 0.76 0
In silico saturation mutagenesis
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Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(MM) Multiple myeloma MM 0.97 0.14