PTEN is detected as a mutational cancer driver
PTEN reports
Gene details
PTEN |
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Ensembl ID
ENSG00000171862
Transcript ID ENST00000371953 Protein ID ENSP00000361021 |
Cancer types where is driver
34
Cohorts where is driver 78 Mutated samples 1,070 Mutations 1,783 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
LUNG_CANCER (Lung) | 3618 | 197 | 5.44 |
UCEC (Endometrial Carcinoma) | 3618 | 534 | 14.76 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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