KRAS is detected as a mutational cancer driver
KRAS reports
Gene details
KRAS |
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Ensembl ID
ENSG00000133703
Transcript ID ENST00000256078 Protein ID ENSP00000256078 |
Cancer types where is driver
33
Cohorts where is driver 84 Mutated samples 2,632 Mutations 2,822 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
ALL (Acute Lymphoblastic Leukemia) | 1692 | 95 | 5.61 |
BLCA (Bladder Urothelial Carcinoma) | 1692 | 130 | 7.68 |
CH (Cholangiocarcinoma) | 1692 | 86 | 5.08 |
COREAD (Colorectal Adenocarcinoma) | 1692 | 67 | 3.96 |
LUAD (Lung Adenocarcinoma) | 1692 | 27 | 1.60 |
LUNG_CANCER (Lung) | 1692 | 27 | 1.60 |
OV (Ovarian Epithelial Tumor) | 1692 | 14 | 0.83 |
PAAD (Pancreatic Adenocarcinoma) | 1692 | 26 | 1.54 |
MM (Plasma Cell Myeloma) | 1692 | 100 | 5.91 |
ST (Stomach Adenocarcinoma) | 1692 | 130 | 7.68 |
UCEC (Endometrial Carcinoma) | 1692 | 64 | 3.78 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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