NF1 is detected as a mutational cancer driver
NF1 reports
Gene details
NF1 |
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Ensembl ID
ENSG00000196712
Transcript ID ENST00000358273 Protein ID ENSP00000351015 |
Cancer types where is driver
27
Cohorts where is driver 53 Mutated samples 638 Mutations 1,695 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BRCA (Invasive Breast Carcinoma) | 25542 | 1113 | 4.36 |
G (Glioblastoma Multiforme) | 25542 | 2578 | 10.09 |
LUAD (Lung Adenocarcinoma) | 25542 | 1323 | 5.18 |
LUNG_CANCER (Lung) | 25542 | 1317 | 5.16 |
CM (Melanoma) | 25542 | 1142 | 4.47 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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