Top
ZNF618 has not been detected as a mutational cancer driver

ZNF618
Ensembl id ENSG00000157657
Mutated samples
Coding Sequence 79 (1.2%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF618 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 10 7 1.87
Cutaneous melanoma No 17 5 1.36
Glioblastoma multiforme No 8 5 1.32
Breast carcinoma No 6 4 0.35
Lung squamous cell carcinoma No 4 4 2.30
Multiple myeloma No 5 4 5.80
Lung adenocarcinoma No 6 3 0.77
Renal clear cell carcinoma No 2 2 0.48
Uterine corpus endometrioid carcinoma No 3 2 0.87
Lower grade glioma No 2 2 1.18
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Stomach adenocarcinoma No 1 1 0.62
Diffuse B cell lymphoma No 2 1 4.35
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence