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ZNF592 has not been detected as a mutational cancer driver

ZNF592
Ensembl id ENSG00000166716
Mutated samples
Coding Sequence 74 (1.1%)
Protein Affecting 51 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF592 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 12 3.25
Breast carcinoma No 11 8 0.70
Lung adenocarcinoma No 7 5 1.28
Head and neck squamous cell carcinoma No 8 5 1.33
Lung squamous cell carcinoma No 4 3 1.72
Renal clear cell carcinoma No 3 3 0.72
Uterine corpus endometrioid carcinoma No 4 3 1.30
Stomach adenocarcinoma No 3 3 1.86
Serous ovarian adenocarcinoma No 4 2 0.63
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 1 1 1.11
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Multiple myeloma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence