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ZNF185 has not been detected as a mutational cancer driver

ZNF185
Ensembl id ENSG00000147394
Mutated samples
Coding Sequence 44 (0.6%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZNF185 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 11 9 2.44
Breast carcinoma No 4 3 0.26
Lung squamous cell carcinoma No 3 3 1.72
Renal clear cell carcinoma No 4 3 0.72
Serous ovarian adenocarcinoma No 3 3 0.95
Thyroid carcinoma No 3 2 0.62
Uterine corpus endometrioid carcinoma No 2 2 0.87
Esophageal carcinoma No 3 2 1.37
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 2 1 1.02
Multiple myeloma No 1 1 1.45
Pylocytic astrocytoma No 1 1 0.99
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence