WNT5A is detected as a mutational cancer driver in 1 cancer type: Prostate adenocarcinoma

Ensembl id ENSG00000114251
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 20 (0.3%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WNT5A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Prostate adenocarcinoma Yes 2 2 0.82
Cutaneous melanoma No 6 3 0.81
Esophageal carcinoma No 7 3 2.05
Breast carcinoma No 4 2 0.17
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Head and neck squamous cell carcinoma No 2 2 0.53
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Chronic lymphocytic leukemia No 2 1 0.34
Renal clear cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence