IntOGen - WNK2 gene cancer mutations

WNK2 is detected as a mutational cancer driver

WNK2 reports

Methods
Mutation distribution

Gene details

WNK2
Gene ID ENSG00000165238 Transcript ID ENST00000427277 Protein ID ENSP00000411181
Cancer types where is driver 3 Cohorts where is driver 4 Mutated samples 12 Mutations 786
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence