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WDR81 has not been detected as a mutational cancer driver

WDR81
Ensembl id ENSG00000167716
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WDR81 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 11 6 1.63
Renal clear cell carcinoma No 5 4 0.96
Uterine corpus endometrioid carcinoma No 5 4 1.74
Stomach adenocarcinoma No 4 4 2.48
Breast carcinoma No 3 3 0.26
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 2 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Lung adenocarcinoma No 2 1 0.26
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Lower grade glioma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence