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TSHZ3 has not been detected as a mutational cancer driver

TSHZ3
Ensembl id ENSG00000121297
Mutated samples
Coding Sequence 180 (2.7%)
Protein Affecting 124 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TSHZ3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 43 34 8.70
Cutaneous melanoma No 24 17 4.61
Lung squamous cell carcinoma No 12 11 6.32
Stomach adenocarcinoma No 14 10 6.21
Breast carcinoma No 13 9 0.78
Uterine corpus endometrioid carcinoma No 16 9 3.91
Colorectal adenocarcinoma No 10 6 2.62
Esophageal carcinoma No 11 6 4.11
Renal clear cell carcinoma No 7 5 1.20
Head and neck squamous cell carcinoma No 6 4 1.07
Serous ovarian adenocarcinoma No 5 3 0.95
Bladder carcinoma No 4 2 2.04
Pancreas adenocarcinoma No 2 2 0.93
Glioblastoma multiforme No 3 2 0.53
Prostate adenocarcinoma No 3 1 0.41
Acute myeloid leukemia No 1 1 0.51
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence