IntOGen - TSHR gene cancer mutations

TSHR is detected as a mutational cancer driver

TSHR reports

Methods
Mutation distribution

Gene details

TSHR
Gene ID ENSG00000165409 Transcript ID ENST00000298171 Protein ID ENSP00000298171
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 8 Mutations 345
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence