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TRPC4AP has not been detected as a mutational cancer driver

TRPC4AP
Ensembl id ENSG00000100991
Mutated samples
Coding Sequence 69 (1.0%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TRPC4AP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 9 7 4.02
Breast carcinoma No 12 4 0.35
Cutaneous melanoma No 16 4 1.08
Renal clear cell carcinoma No 4 2 0.48
Uterine corpus endometrioid carcinoma No 5 2 0.87
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 4 1 1.02
Acute myeloid leukemia No 1 1 0.51
Chronic lymphocytic leukemia No 1 1 0.34
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 4 1 0.27
Glioblastoma multiforme No 3 1 0.26
Serous ovarian adenocarcinoma No 3 0 0.00
Stomach adenocarcinoma No 3 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence