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TRIM3 has not been detected as a mutational cancer driver

TRIM3
Ensembl id ENSG00000110171
Mutated samples
Coding Sequence 68 (1.0%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TRIM3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 8 2.17
Lung adenocarcinoma No 9 6 1.53
Uterine corpus endometrioid carcinoma No 5 4 1.74
Stomach adenocarcinoma No 6 3 1.86
Lung squamous cell carcinoma No 3 2 1.15
Renal clear cell carcinoma No 4 2 0.48
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 2 2 0.53
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Head and neck squamous cell carcinoma No 1 1 0.27
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 4 0 0.00
Thyroid carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence