TP53 is detected as a mutational cancer driver

TP53 reports

Gene details
Ensembl ID ENSG00000141510
Transcript ID ENST00000269305
Protein ID ENSP00000269305
Cancer types where is driver 52
Cohorts where is driver 165
Mutated samples 7,695
Mutations 8,504
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence