IntOGen - TMPRSS2 gene cancer mutations

TMPRSS2 is detected as a mutational cancer driver

TMPRSS2 reports

Methods
Mutation distribution

Gene details

TMPRSS2
Gene ID ENSG00000184012 Transcript ID ENST00000332149 Protein ID ENSP00000330330
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 3 Mutations 238
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence