IntOGen - TET2 gene cancer mutations

TET2 is detected as a mutational cancer driver

TET2 reports

Methods
Mutation distribution

Gene details

TET2
Gene ID ENSG00000168769 Transcript ID ENST00000380013 Protein ID ENSP00000369351
Cancer types where is driver 7 Cohorts where is driver 9 Mutated samples 50 Mutations 588
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence