SMAD2 is detected as a mutational cancer driver

SMAD2 reports

Gene details
Ensembl ID ENSG00000175387
Transcript ID ENST00000262160
Protein ID ENSP00000262160
Cancer types where is driver 1
Cohorts where is driver 3
Mutated samples 28
Mutations 152
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence