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SAFB has not been detected as a mutational cancer driver

SAFB
Ensembl id ENSG00000160633
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SAFB gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 8 2.17
Uterine corpus endometrioid carcinoma No 7 7 3.04
Breast carcinoma No 6 4 0.35
Head and neck squamous cell carcinoma No 5 4 1.07
Lung squamous cell carcinoma No 6 3 1.72
Lung adenocarcinoma No 2 2 0.51
Hepatocarcinoma No 2 2 2.22
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence