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RPS6KA3 is detected as a mutational cancer driver

RPS6KA3 reports

Gene details
RPS6KA3
Ensembl ID ENSG00000177189
Transcript ID ENST00000645845
Protein ID ENSP00000494131
Cancer types where is driver 1
Cohorts where is driver 4
Mutated samples 36
Mutations 209
Mode of action Loss of function
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence