IntOGen - ROBO2 gene cancer mutations

ROBO2 is detected as a mutational cancer driver

ROBO2 reports

Methods
Mutation distribution

Gene details

ROBO2
Gene ID ENSG00000185008 Transcript ID ENST00000696593 Protein ID ENSP00000512738
Cancer types where is driver 11 Cohorts where is driver 16 Mutated samples 95 Mutations 1,217
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence