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RNF43 is detected as a mutational cancer driver

RNF43 reports

Gene details
RNF43
Ensembl ID ENSG00000108375
Transcript ID ENST00000584437
Protein ID ENSP00000463069
Cancer types where is driver 6
Cohorts where is driver 12
Mutated samples 78
Mutations 320
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence