RNF213 is detected as a mutational cancer driver

RNF213 reports

Gene details
Ensembl ID ENSG00000173821
Transcript ID ENST00000582970
Protein ID ENSP00000464087
Cancer types where is driver 7
Cohorts where is driver 7
Mutated samples 25
Mutations 974
Mode of action Activating
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence