Top
PTPRC has not been detected as a mutational cancer driver

PTPRC
Ensembl id ENSG00000081237
Mutated samples
Coding Sequence 162 (2.4%)
Protein Affecting 123 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PTPRC gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 47 36 9.76
Lung adenocarcinoma No 24 19 4.86
Head and neck squamous cell carcinoma No 19 14 3.73
Stomach adenocarcinoma No 12 9 5.59
Breast carcinoma No 8 6 0.52
Lung squamous cell carcinoma No 8 5 2.87
Renal clear cell carcinoma No 6 5 1.20
Bladder carcinoma No 4 4 4.08
Small cell lung carcinoma No 4 4 5.80
Esophageal carcinoma No 4 4 2.74
Prostate adenocarcinoma No 4 3 1.23
Uterine corpus endometrioid carcinoma No 3 3 1.30
Serous ovarian adenocarcinoma No 3 3 0.95
Lower grade glioma No 2 2 1.18
Glioblastoma multiforme No 5 2 0.53
Hepatocarcinoma No 3 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Chronic lymphocytic leukemia No 2 1 0.34
Colorectal adenocarcinoma No 2 1 0.44
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence