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PSG4 has not been detected as a mutational cancer driver

PSG4
Ensembl id ENSG00000243137
Mutated samples
Coding Sequence 70 (1.0%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PSG4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 36 25 6.78
Lung adenocarcinoma No 6 5 1.28
Head and neck squamous cell carcinoma No 4 4 1.07
Breast carcinoma No 3 2 0.17
Lung squamous cell carcinoma No 4 2 1.15
Colorectal adenocarcinoma No 3 2 0.87
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Medulloblastoma No 1 1 0.48
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 2 1 0.26
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence