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PRKAR1A is detected as a mutational cancer driver

PRKAR1A reports

Gene details
PRKAR1A
Ensembl ID ENSG00000108946
Transcript ID ENST00000392711
Protein ID ENSP00000376475
Cancer types where is driver 3
Cohorts where is driver 4
Mutated samples 16
Mutations 116
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence