IntOGen - PREX2 gene cancer mutations

PREX2 is detected as a mutational cancer driver

PREX2 reports

Methods
Mutation distribution

Gene details

PREX2
Gene ID ENSG00000046889 Transcript ID ENST00000288368 Protein ID ENSP00000288368
Cancer types where is driver 12 Cohorts where is driver 13 Mutated samples 159 Mutations 1,501
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence