IntOGen - POU2F2 gene cancer mutations

POU2F2 is detected as a mutational cancer driver

POU2F2 reports

Methods
Mutation distribution

Gene details

POU2F2
Ensembl ID ENSG00000028277 Transcript ID ENST00000526816 Protein ID ENSP00000431603
Cancer types where is driver 3 Cohorts where is driver 4 Mutated samples 23 Mutations 257
Mode of action Ambiguous
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence