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POU2F2 has not been detected as a mutational cancer driver

POU2F2
Ensembl id ENSG00000028277
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all POU2F2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 10 2.71
Head and neck squamous cell carcinoma No 4 4 1.07
Breast carcinoma No 6 3 0.26
Lung adenocarcinoma No 2 2 0.51
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 2 2 1.24
Thyroid carcinoma No 1 1 0.31
Colorectal adenocarcinoma No 1 1 0.44
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence