IntOGen - PLAG1 gene cancer mutations

PLAG1 is detected as a mutational cancer driver

PLAG1 reports

Methods
Mutation distribution

Gene details

PLAG1
Ensembl ID ENSG00000181690 Transcript ID ENST00000316981 Protein ID ENSP00000325546
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 10 Mutations 253
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence