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PIK3R1 is detected as a mutational cancer driver

PIK3R1 reports

Gene details
PIK3R1
Ensembl ID ENSG00000145675
Transcript ID ENST00000521381
Protein ID ENSP00000428056
Cancer types where is driver 10
Cohorts where is driver 14
Mutated samples 218
Mutations 331
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence