Top
PCDHGC3 has not been detected as a mutational cancer driver

PCDHGC3
Ensembl id ENSG00000240184
Mutated samples
Coding Sequence 132 (1.9%)
Protein Affecting 34 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHGC3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 34 8 2.17
Lung adenocarcinoma No 13 4 1.02
Head and neck squamous cell carcinoma No 12 4 1.07
Breast carcinoma No 9 3 0.26
Stomach adenocarcinoma No 10 3 1.86
Prostate adenocarcinoma No 3 2 0.82
Bladder carcinoma No 5 2 2.04
Uterine corpus endometrioid carcinoma No 7 2 0.87
Colorectal adenocarcinoma No 7 2 0.87
Glioblastoma multiforme No 3 2 0.53
Serous ovarian adenocarcinoma No 6 1 0.32
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 6 0 0.00
Renal clear cell carcinoma No 5 0 0.00
Thyroid carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence