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PCDHGA7 has not been detected as a mutational cancer driver

PCDHGA7
Ensembl id ENSG00000253537
Mutated samples
Coding Sequence 662 (9.7%)
Protein Affecting 65 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHGA7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 133 15 4.07
Lung adenocarcinoma No 68 10 2.56
Stomach adenocarcinoma No 41 7 4.35
Head and neck squamous cell carcinoma No 69 7 1.87
Uterine corpus endometrioid carcinoma No 49 6 2.61
Bladder carcinoma No 27 4 4.08
Breast carcinoma No 54 4 0.35
Lung squamous cell carcinoma No 45 3 1.72
Serous ovarian adenocarcinoma No 21 2 0.63
Colorectal adenocarcinoma No 26 2 0.87
Esophageal carcinoma No 33 2 1.37
Medulloblastoma No 4 1 0.48
Lower grade glioma No 9 1 0.59
Glioblastoma multiforme No 24 1 0.26
Prostate adenocarcinoma No 12 0 0.00
Hepatocarcinoma No 3 0 0.00
Acute myeloid leukemia No 3 0 0.00
Pancreas adenocarcinoma No 4 0 0.00
Renal clear cell carcinoma No 18 0 0.00
Thyroid carcinoma No 5 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
Multiple myeloma No 3 0 0.00
Small cell lung carcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Acute lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence