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PCDHA11 has not been detected as a mutational cancer driver

PCDHA11
Ensembl id ENSG00000249158
Mutated samples
Coding Sequence 503 (7.4%)
Protein Affecting 102 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDHA11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 137 32 8.67
Lung adenocarcinoma No 48 12 3.07
Uterine corpus endometrioid carcinoma No 38 9 3.91
Breast carcinoma No 37 8 0.70
Stomach adenocarcinoma No 40 8 4.97
Head and neck squamous cell carcinoma No 51 8 2.13
Lung squamous cell carcinoma No 15 5 2.87
Bladder carcinoma No 15 3 3.06
Lower grade glioma No 7 3 1.78
Hepatocarcinoma No 2 2 2.22
Serous ovarian adenocarcinoma No 9 2 0.63
Colorectal adenocarcinoma No 22 2 0.87
Glioblastoma multiforme No 19 2 0.53
Esophageal carcinoma No 19 2 1.37
Pancreas adenocarcinoma No 3 1 0.47
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 8 1 0.34
Small cell lung carcinoma No 2 1 1.45
Prostate adenocarcinoma No 8 0 0.00
Acute myeloid leukemia No 2 0 0.00
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 11 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Multiple myeloma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Acute lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence