MYD88 is detected as a mutational cancer driver in 1 cancer type: Chronic lymphocytic leukemia

Ensembl id ENSG00000172936
Mutated samples
Coding Sequence 34 (0.5%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver Yes
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MYD88 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Chronic lymphocytic leukemia Yes 15 15 5.17
Cutaneous melanoma No 6 4 1.08
Lung adenocarcinoma No 3 2 0.51
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 1 1 0.27
Breast carcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence