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MOV10L1 has not been detected as a mutational cancer driver

MOV10L1
Ensembl id ENSG00000073146
Mutated samples
Coding Sequence 100 (1.5%)
Protein Affecting 71 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MOV10L1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 38 28 7.59
Lung adenocarcinoma No 11 9 2.30
Lung squamous cell carcinoma No 6 6 3.45
Breast carcinoma No 8 5 0.44
Renal clear cell carcinoma No 3 3 0.72
Stomach adenocarcinoma No 4 3 1.86
Head and neck squamous cell carcinoma No 4 3 0.80
Glioblastoma multiforme No 4 3 0.79
Bladder carcinoma No 4 2 2.04
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 3 2 0.63
Colorectal adenocarcinoma No 4 2 0.87
Thyroid carcinoma No 1 1 0.31
Chronic lymphocytic leukemia No 3 1 0.34
Small cell lung carcinoma No 2 1 1.45
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence