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KRT27 has not been detected as a mutational cancer driver

KRT27
Ensembl id ENSG00000171446
Mutated samples
Coding Sequence 52 (0.8%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KRT27 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 7 6 3.73
Cutaneous melanoma No 13 4 1.08
Uterine corpus endometrioid carcinoma No 4 3 1.30
Lung squamous cell carcinoma No 2 2 1.15
Head and neck squamous cell carcinoma No 4 2 0.53
Prostate adenocarcinoma No 4 1 0.41
Acute myeloid leukemia No 1 1 0.51
Renal clear cell carcinoma No 1 1 0.24
Neuroblastoma No 1 1 0.48
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 2 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Lung adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Breast carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence