IntOGen - KNSTRN gene cancer mutations

KNSTRN is detected as a mutational cancer driver

KNSTRN reports

Methods
Mutation distribution

Gene details

KNSTRN
Ensembl ID ENSG00000128944 Transcript ID ENST00000249776 Protein ID ENSP00000249776
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 13 Mutations 157
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence