IntOGen - KLHL6 gene cancer mutations

KLHL6 is detected as a mutational cancer driver

KLHL6 reports

Methods
Mutation distribution

Gene details

KLHL6
Gene ID ENSG00000172578 Transcript ID ENST00000341319 Protein ID ENSP00000341342
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 18 Mutations 418
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence