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KDM4C has not been detected as a mutational cancer driver

KDM4C
Ensembl id ENSG00000107077
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KDM4C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 9 7 1.79
Breast carcinoma No 7 5 0.44
Head and neck squamous cell carcinoma No 5 4 1.07
Cutaneous melanoma No 9 3 0.81
Lung squamous cell carcinoma No 4 2 1.15
Uterine corpus endometrioid carcinoma No 5 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 4 2 1.24
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Hepatocarcinoma No 2 0 0.00
Bladder carcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence