IntOGen - KAT6B gene cancer mutations

KAT6B is detected as a mutational cancer driver

KAT6B reports

Methods
Mutation distribution

Gene details

KAT6B
Ensembl ID ENSG00000156650 Transcript ID ENST00000287239 Protein ID ENSP00000287239
Cancer types where is driver 5 Cohorts where is driver 5 Mutated samples 18 Mutations 616
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence