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JAK3 is detected as a mutational cancer driver

JAK3 reports

Gene details
JAK3
Ensembl ID ENSG00000105639
Transcript ID ENST00000458235
Protein ID ENSP00000391676
Cancer types where is driver 1
Cohorts where is driver 1
Mutated samples 4
Mutations 329
Mode of action Activating
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence