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JAK2 is detected as a mutational cancer driver

JAK2 reports

Gene details
JAK2
Ensembl ID ENSG00000096968
Transcript ID ENST00000381652
Protein ID ENSP00000371067
Cancer types where is driver 3
Cohorts where is driver 3
Mutated samples 12
Mutations 237
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence