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JAK2 is detected as a mutational cancer driver

JAK2 reports

Gene details
JAK2
Ensembl ID ENSG00000096968
Transcript ID ENST00000381652
Protein ID ENSP00000371067
Cancer types where is driver 3
Cohorts where is driver 4
Mutated samples 14
Mutations 252
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence