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ITGA2 has not been detected as a mutational cancer driver

ITGA2
Ensembl id ENSG00000164171
Mutated samples
Coding Sequence 76 (1.1%)
Protein Affecting 53 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ITGA2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 12 11 2.81
Cutaneous melanoma No 16 11 2.98
Lung squamous cell carcinoma No 6 5 2.87
Breast carcinoma No 5 4 0.35
Head and neck squamous cell carcinoma No 6 4 1.07
Bladder carcinoma No 5 3 3.06
Stomach adenocarcinoma No 3 3 1.86
Neuroblastoma No 2 2 0.95
Uterine corpus endometrioid carcinoma No 3 2 0.87
Colorectal adenocarcinoma No 3 2 0.87
Esophageal carcinoma No 2 2 1.37
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence