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INPP4B has not been detected as a mutational cancer driver

INPP4B
Ensembl id ENSG00000109452
Mutated samples
Coding Sequence 86 (1.3%)
Protein Affecting 56 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all INPP4B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 14 12 3.07
Head and neck squamous cell carcinoma No 7 7 1.87
Breast carcinoma No 6 5 0.44
Uterine corpus endometrioid carcinoma No 6 5 2.17
Cutaneous melanoma No 5 4 1.08
Bladder carcinoma No 4 3 3.06
Medulloblastoma No 3 3 1.43
Lung squamous cell carcinoma No 3 3 1.72
Small cell lung carcinoma No 3 3 4.35
Renal clear cell carcinoma No 2 2 0.48
Chronic lymphocytic leukemia No 14 2 0.69
Stomach adenocarcinoma No 4 2 1.24
Hepatocarcinoma No 4 1 1.11
Non small cell lung carcinoma No 2 1 3.23
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 1 1 0.26
Pylocytic astrocytoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence