IntOGen - IL7R gene cancer mutations

IL7R is detected as a mutational cancer driver

IL7R reports

Methods
Mutation distribution

Gene details

IL7R
Ensembl ID ENSG00000168685 Transcript ID ENST00000303115 Protein ID ENSP00000306157
Cancer types where is driver 3 Cohorts where is driver 3 Mutated samples 14 Mutations 461
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence