Top

IDH2 is detected as a mutational cancer driver

IDH2 reports

Gene details
IDH2
Ensembl ID ENSG00000182054
Transcript ID ENST00000330062
Protein ID ENSP00000331897
Cancer types where is driver 5
Cohorts where is driver 8
Mutated samples 78
Mutations 178
Mode of action Activating
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence