IntOGen - HLA-A gene cancer mutations

HLA-A is detected as a mutational cancer driver

HLA-A reports

Methods
Mutation distribution

Gene details

HLA-A
Gene ID ENSG00000206503 Transcript ID ENST00000376809 Protein ID ENSP00000366005
Cancer types where is driver 14 Cohorts where is driver 20 Mutated samples 127 Mutations 417
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence