IntOGen - GRIN2A gene cancer mutations

GRIN2A is detected as a mutational cancer driver

GRIN2A reports

Methods
Mutation distribution

Gene details

GRIN2A
Ensembl ID ENSG00000183454 Transcript ID ENST00000330684 Protein ID ENSP00000332549
Cancer types where is driver 12 Cohorts where is driver 13 Mutated samples 175 Mutations 1,576
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence